Running Head: BIOSTATISTICS IN NURSING: FINAL PAPER
Biostatistics in Nursing: Final Paper
Nova Southeastern University
Marcia Derby RN, MSN, Asst Prof.
October 15, 2008
Many people develop renal disease and once they become diagnosed with End Stage Renal Disease many have only a few choices when it comes to renal replacement modalities. According to Chapman, M., Fink, N., Finkelstein, F., Marsh, J., Meyer, K., Powe, N., Wu, A. (2004), every year in the United States, nearly 90,000 patients with chronic kidney disease progress to ESRD and begin renal replacement therapy. Most patients optimally would prefer a kidney transplant, ...view middle of the document...
With regards to health related quality of life, there are advantages and disadvantages with each type of therapy. Each patient must base their decision on factors such as how they can incorporate either modality into their particular lifestyle, how involved they want to become with regards to self-care, and/or if they want to get stuck with a needle every few days, and even there abilities and attitudes must be taken into consideration when choosing between modalities. These are just a few of the factors that an ESRD patient must make a decision from, which will then eventually affect their quality of life. So the problem in question here is which renal replacement therapy provides a better quality of life and which modality of renal replacement therapy do ESRD patients prefer? With statistical analysis of the variability’s between these two groups of patients a null hypothesis that can be produced would be, there is no difference between the qualities of life of ESRD patients on hemodialysis and peritoneal dialysis.
Review of the Literature
The articles selected to help identify and clarify the research into this question came from a few different journals that specialize in the aspects of nephrology, such as the Journal of the American Society of Nephrology, The Institute of Nephrology and Hemodialysis: Artificial Organs, and the Journal of Nephrology, Dialysis, and Transplantation. Each article was chosen because they contained research information specifically about ESRD patients and the quality of their lives, with regards to the type of renal replacement therapy that they chose. Each journal article was broken down into background information for research, methods used for obtaining research data, the results of the analyzed data. Two articles had at least five dimensions of analysis specific domains and one article had eight. Much of data that was collected included variables that consisted of sociodemographic information, such as age, race, gender, employment, duration of dialysis treatment, limitations on usual activities, bodily pain, laboratory values, and general health perceptions, to name a few. These articles were chosen primarily because they contain statistical factual information and are peer reviewed.
The population of interest for this study included End Stage Renal Disease patients, and the two groups that were chosen and compared were on either hemodialysis or peritoneal dialysis. This population was chosen based on the history and knowledge acquired from the specific care given to these types of patients on the units that I worked. The samples of the population that were assessed in these studies were given questionnaires to fill out so that pertinent data could be collected. One study used the EQ-5D, which was developed by the international EuroQol group as a standardized generic measure for description of health status according to Wasserfallen, J., Halabi, G., Saudan, P., Perneger, T., Feldman, H. Martin,...