Cystic Fibarosis Pathology Paper

663 words - 3 pages

Cystic fibrosis is an autosomal recessive disorder that affects the function of the exocrine glands in multiple organ systems, mainly resulting in chronic respiratory infections and insufficient pancreatic enzymes. Cystic fibrosis is caused by mutations of two gene pairs, one from mom and one from dad, on chromosome 7. However, if the person inherits mutations on just one gene they don’t actually have the disease but they are a carrier of Cystic fibrosis.

Chromosome 7 produces a protein called CF transmemebrane regulator. CF transmembrane regulator is responsible for regulating the channels of sodium and chloride, but when there are mutations on the gene the channels become blocked. ...view middle of the document...

This type of diabetes is unique because it has characteristics of both Type 1 and Type 2. When a person has CF, the pancreas is still able to release some insulin but it is never enough to manage the carbohydrate intake. Therefore, insulin is needed to manage CFRD.

CF is usually diagnosed in infants. A few children with CF begin having symptoms at birth. It is noticed at birth because the child is unable to pass the meconium because it is thicker and sticker than that of a baby without CF. This causes the meconium to completely block the intestines. Also, because the baby’s enzymes are not absorbing the fat in its intestines his or her soiled diapers will appear fatty which may alarm the parents into thinking something is wrong.

Parents may also notice that when they kiss their baby they may taste “salty”. This is because when a child has CF, sodium and chloride can’t be absorbed as the sweat moves through the ducts causing about four times the amount of sodium and chloride in the sweat.

Meds commonly...

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